MD Anderson Cancer Center: NK cells in the treatment of lymphoma, the objective response rate can reach 100%!


Release date:

2021-12-06

Recently, MD Anderson Cancer Center announced a new study: in patients with previously treated refractory CD30-positive lymphoma, the use of NK cells extracted from donated umbilical cord blood, combined with a target CD16A and CD30. of the novel bispecific antibody AFM13, with an overall response rate of 89%, including 10 complete responses. AFM13, a first-in-class innate cell engager (ICE), is a bispecific tetravalent antibody targeting CD30 and CD16 that specifically binds CD30 on tumor cells and innate immune cells such as NK cells and macrophages ) on CD16A.

Recently, MD Anderson Cancer Center announced a new study: in patients with previously treated refractory CD30-positive lymphoma, the use of NK cells extracted from donated umbilical cord blood, combined with a target CD16A and CD30. of the novel bispecific antibody AFM13, with an overall response rate of 89%, including 10 complete responses. AFM13, a first-in-class innate cell engager (ICE), is a bispecific tetravalent antibody targeting CD30 and CD16 that specifically binds CD30 on tumor cells and innate immune cells such as NK cells and macrophages ) on CD16A.


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